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Kawthar Alghamdi


Kawthar Alghamdi

UCD Conway Institute - University College Dublin, Ireland

Biography

Kawthar Alghamdi is pursuing her final year PhD in the School of Biomolecular and Biomedical Science, University College Dublin, Ireland under the supervision of Associate Professor Orina Belton. She received her MSc in Biotechnology from University College Dublin in 2013. Her previous work in the atherosclerosis research group at University College Dublin has shown that dietary administration of conjugated linoleic acid induces the regression of pre-established atherosclerosis via altering monocyte function. Her recent research has focused on the identification of distinct pathways regulated by conjugated linoleic acid that may yield further information as to how atherosclerosis can be reversed. To do this she has employed a comprehensive proteomic approach, to construct networks and identify key signaling pathways associated with altered monocyte/macrophage fate and function. Through this work she has identified and validated that TGFβ signaling mediates the atheroprotective effect of CLA.

Abstract

Abstract : Conjugated linoleic acid induces TGFβ signalling regulate macrophage fate